https://www.ncbi.nlm.nih.gov › pmc › articles › PMC5680136
Chitin and Its Effects on Inflammatory and Immune Responses
Increased secretion of chitinases is closely associated with pathophysiological conditions dominated by T-helper type 2 cells (Th2) including infection, fibrosis, allergy, and asthma [ 64, 65 ]. Chitin exposure directly …
Chitin and Its Effects on Inflammatory and Immune Responses
Increased secretion of chitinases is closely associated with pathophysiological conditions dominated by T-helper type 2 cells (Th2) including infection, fibrosis, allergy, and asthma [ 64, 65 ]. Chitin exposure directly stimulates expression of the pro-Th2 mediators AMCase and eotaxin-3 in cultures of sinonasal epithelial cells [ 66 ].
The potential role of chitin in allergic reactions - ScienceDirect
Allergic immune response to chitin or the helminth N. brasiliensis in the lung. Infection with helminths or chitin alternatively activates macrophages, causing upregulation of chitinolytic and chitin-binding proteins. Secretion of leukotriene B 4 recruits innate immune cells such as eosinophils and basophils, and might initiate a Th2 response.
Chitin, a structural molecule associated with allergy response, is ...
An unexpected discovery overturns a longstanding belief in the biological sciences. The research demonstrates that chitin, a molecule that was previously thought to be absent in vertebrates and...
Chitin, Chitinases and Chitinase-like Proteins in Allergic Inflammation ...
When viewed in combination, chitin or allergen modulated the expression of chitinases or chitin-binding proteins, and these chitinases may have a direct protective role against chitin by degrading the chitin itself, but also may function to amplify inflammatory responses against chitin or other allergens.
https://www.ncbi.nlm.nih.gov › pmc › articles › PMC5680136
Chitin and Its Effects on Inflammatory and Immune Responses
Increased secretion of chitinases is closely associated with pathophysiological conditions dominated by T-helper type 2 cells (Th2) including infection, fibrosis, allergy, and asthma [ 64, 65 ]. Chitin exposure directly stimulates expression of the pro-Th2 mediators AMCase and eotaxin-3 in cultures of sinonasal epithelial cells [ 66 ].
https://www.sciencedirect.com › science › article › pii › S1471490607002086
The potential role of chitin in allergic reactions - ScienceDirect
Allergic immune response to chitin or the helminth N. brasiliensis in the lung. Infection with helminths or chitin alternatively activates macrophages, causing upregulation of chitinolytic and chitin-binding proteins. Secretion of leukotriene B 4 recruits innate immune cells such as eosinophils and basophils, and might initiate a Th2 response.
https://www.sciencedaily.com › releases › 2015 › 03 › 150313171148.htm
Chitin, a structural molecule associated with allergy response, is ...
An unexpected discovery overturns a longstanding belief in the biological sciences. The research demonstrates that chitin, a molecule that was previously thought to be absent in vertebrates and...
https://www.ncbi.nlm.nih.gov › pmc › articles › PMC2649864
Chitin, Chitinases and Chitinase-like Proteins in Allergic Inflammation ...
When viewed in combination, chitin or allergen modulated the expression of chitinases or chitin-binding proteins, and these chitinases may have a direct protective role against chitin by degrading the chitin itself, but also may function to amplify inflammatory responses against chitin or other allergens.